The famous blue people of Kentucky are no longer blue. But why were they like that in the first place?
# Stuff You Should Know Episode Summary
Join Josh and Chuck as they dive into the fascinating and unusual medical condition of methemoglobinemia, which causes people to literally have blue skin. They trace the history of the famous "blue Fugates" of Kentucky, a family whose rare genetic mutation, combined with isolated mountain living and subsequent inbreeding, resulted in multiple generations of blue-skinned individuals. The episode also explores related conditions like argyria, caused by excessive silver consumption, and covers how a determined hematologist named Madison Cawein discovered a simple pill treatment that could reverse the blueness in minutes, transforming the lives of these families who had hidden away in shame for generations.
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