May 28 2020

How Narcolepsy Works

52 min 3 movies discussed
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Narcolepsy is one of those amazing rare disorders that everyone thinks they understand – people just fall asleep at random times, even in the middle of doing something. But there’s a lot more to it and – even better – we actually may be able to explain it.

AI Summary

# Stuff You Should Know: Narcolepsy

Josh and Chuck dive deep into narcolepsy, exploring how this chronic sleep disorder affects roughly one in 2,000 people with far more complexity than most realize. Beyond the famous sleep attacks, they unpack the lesser-known symptoms like cataplexy (sudden muscle paralysis), sleep paralysis, and terrifying hallucinations that can make narcolepsy genuinely frightening and disruptive to daily life. The episode takes a fascinating turn when they reveal the breakthrough discovery in the 1990s of hypocretin, a brain chemical responsible for keeping us awake, and how an autoimmune response may be the real culprit behind narcolepsy—with a stunning connection to a swine flu vaccine that inadvertently triggered cases in children.


Movies Discussed

Cats
Cats
1998 2h 0m
★ 7.3
"Don't you remember that I tried to make myself go to sleep in cats in the middle of the cats? — Josh jokingly suggests the Cats movie is so boring it puts people to sleep, comparing it to narcolepsy." — Josh
My Own Private Idaho
My Own Private Idaho
1991 R 1h 44m
★ 7.0
"The closest I've come to that is watching my own private Idaho. — Chuck references the film when discussing narcolepsy, mentioning it stars River Phoenix or Keanu Reeves who may have narcolepsy." — Chuck
Soul Train
Soul Train
1971
★ 8.0
"We really enjoyed your Soul Train episode. You did a great job capturing the feeling and cultural significance of the show. — A listener writes in with positive feedback about the podcast's previous Soul Train episode."

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